After a scrappy first half, it was Preston who took the lead as Alan Browne headed beyond John Ruddy in the 52nd minute.
The hosts then had John Welsh sent off just minutes later for a second bookable offence as he fouled Ivan Cavaleiro.
It was Wolves who looked like the only team who was going to win the game as Helder Costa’s volley drew the visitors level.
Preston proved a tough defensive unit as they were able to keep Wolves out meaning both sides going home with a point.
Nuno praised the attitude of his players and thanked the 5,626 travelling Wolves fans for their support.
He said, “We knew that it was going to be a tough game.
“In the first half, well played to both teams. We created chances but Preston also.
“The second half is something we have to look at, I think we’re in control of the game and a set piece changes that.
“But the reaction was good, the boys worked well, good support from our fans, we prepare every game to win and of course we are not happy but the attitude was good.
“The reaction was good and we wanted to win the game.
“The boys tried, I think we created chances and things will come naturally but it was a tough game.
“At the same time, we want to win the game so your heart starts controlling your decisions.
“I think we have to be proud of ourselves with the 5,600 people shouting - at the end getting the reward of the applause, thank you for them and we prepare for Norwich.”
Nuno continued to explain why his side were unable to find a solution to win the game against the ten men of Preston.
He called for his side to be more patience, however he also gave credit to the hosts credit for defending well.
“We have to give credit to Preston because they defend well - we know that when they have one man less, the space is reduced and it requires more patience,” Nuno said.
“With ten men, you see that you are in control of the game as you have one man more and you sometimes rush yourself.
“At the same time, the spaces are not there because Preston dropped and didn’t do anything, of course understandably.
“We have to recognise that and it requires a different game - a game of patience and then the spaces will come, that’s something that we have to look at but we prepare always to play against 11.
“I think we were the better team today, I think we were closer to the victory and if we won, nobody would be surprised.
“I’m not happy, I went to the dressing room and the boys are down and we don’t have to be.
“We have to be proud because we did everything that we could do in the game but we didn’t win today.
“Let’s try and win the next one.”
Wolves’ next fixture is at home to Norwich City in the Sky Bet Championship on Wednesday evening (7.45pm).